Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1990-08-10
1991-11-26
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514781, 514912, 514915, A61K 31715, A61K 4700
Patent
active
050682253
ABSTRACT:
This invention relates to an improved viscoelastic fluid or gel for use in surgery and other therapies which consists of polyethylene oxide in selected concentrations not to exceed approximately 15% (15,000 ppm), contained in a physiologic balanced salt solution. The PEO may also be used in conjunction with viscosity enhancers which also act as heat stabilizers such as methylcellulose and its derivatives, polyvinyl pyrrolidone of polyvinyl alcohol or in conjunction with elasticizes such as low molecular weight polyethylene glycols or polypropylene glycols or in conjunction with gelation modifiers. These mixtures may be modified to increase retention time in the body by crosslinking with the use of material like dimethyl urea. The invention encompasses the novel method of protecting and lubricating the corneal tissues during surgery with uses of different concentrations of the same solution introduced simultaneously to protect the inner cornea while periodically irrigating the outer cornea, all without obscuring the surgeon's view of the site. This invention also prevents the development of wound adhesion and has many utilizations in orthopedics.
REFERENCES:
patent: 3856919 (1974-12-01), Rankin
patent: 3947573 (1975-03-01), Rankin
patent: 4629623 (1986-12-01), Balazes
Neurosurg. 13:367-370, 1983.
Am J. Obstet. Gynecol. 136:173-178, 1980.
J. Surg. Res. 45:44-49, 1988.
Fertil Serial 41:926-932, 1984.
Handbook of Non-Prescription Drugs, Eight Edition (1989), pub. American Pharmaceutical Association.
Am Intraocular Implant Soc. J-vol. 6, pp. 28-29, Jan. 1980.
Am Intraocular Implant Soc. J-vol. 6, pp. 129-136, Apr. 1980.
Clin. Orthop. 115:92-95, 1976.
J. Bone Joint Surg. 56B:545-550, 1974.
Am J. Obstet Gynecol. 159:957-963, 1988.
J. Reprod. Med 32:812-814, 1987.
Surg. 94:336-341, 1983.
Am J. Obstet Gynecol 155:667-670, 1986.
J. Neurosurg. 60:1022-1028, 1984.
Plast. Reconstr. Surg. 48:256-259, 1971.
Allen Mark D.
Blackmore John M.
Pennell Phillip E.
Fay Zohreh A.
MDR Group, Inc.
Waddell Frederick E.
LandOfFree
Viscoelastic fluid for use in surgery and other therapies and me does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Viscoelastic fluid for use in surgery and other therapies and me, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Viscoelastic fluid for use in surgery and other therapies and me will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2386009