Virus inhibiting composition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Lignin or derivative doai

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4241951, 514 54, 530500, 530501, 530502, 530506, 536 111, 536121, 536124, 5361231, A61K 3170, C07G 100, C08L 9700

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active

055545963

ABSTRACT:
A composite molecular active substance group for use in restitutive chemotherapy against viral infections, which is produced by the process comprising: (a) preparing lignin units by carrying out an extraction in an aqueous media under weakly acidic or alkaline conditions of wood or wood-like materials and/or plant-cell cultures and separating-off the resultant insoluble solids; (b) preparing lignoid units by carrying out an aqueous alkaline extraction at a pH of 7 to 14 of starting materials selected from the group consisting of wood-incarbonization products and bioconverted wood-like materials and separating-off the resultant alkali-insoluble solids; and (c) preparing a water-soluble mixed polymer by reacting the lignin units from step (a) with the lignoid units from step (b), under aqueous alkaline isolating by ultrafiltration a low molecular weight fraction having a molecular weight of no more than 3000 daltons of the mixed polymer, taking a cut between 15 to 40 kilodaltons and discarding the resultant residue, and treating the resultant solution with an H.sup.+ cation exchanger at a pH of 3 to 7 and then carrying out further processing.

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Derwent WPI English abstract, accession No. 91-012374 [02], of Japanese patent publication 2 286 623 of Nov. 26, 1990, based on Japanese application 89 0 108 116 of Apr. 27, 1989, entitled "Anti-Viral Substance", assigned Noda Syokukin Kogyo.
Nicholas Hahon et al./U.S Public Health Service, Morgantown WV "Effects of Lignite Fly Ash Particulates and Soluble Components on the Interferon System," in journal Environmental Research, vol. 32, No. 2, pp. 329-343, pub. Dec. 1983 by Academic Press.

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