Virus inactivating diluents used in immunoassays

Details Virus inactivating diluents used in immunoassays Virus inactivating diluents used in immunoassays

1987-06-30

1989-06-13

Rosen, Sam

Chemistry: analytical and immunological testing

Including sample preparation

Digestion or removing interfering materials

436174, 436176, 436820, 436 22, 436536, 424 89, 424101, 435 5, 435 7, 435238, G01N 100

Patent

active

048392987

ABSTRACT:
Diluent compositions for preparing specimens for immunoassay contain effective amounts of salt and non-ionic surfactants to inactivate viruses in the specimens and improve the sensitivity and specificity of the immunoassays; said diluents having some strengths of from about 21 to about 35 mS/cm and comprising 0.05 to 1% non-ionic surfactants, along with other conventional ingredients. The invention relates as well to immunoassay procedures using the novel diluents.

REFERENCES:
patent: 4314997 (1982-02-01), Shanbrom
patent: 4613501 (1986-09-01), Horowitz
patent: 4619896 (1986-10-01), Shattock et al.
patent: 4645666 (1987-02-01), Manning et al.

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