Virus-inactivated factor Xa preparation

Details Virus-inactivated factor Xa preparation Virus-inactivated factor Xa preparation

1994-08-02

1997-01-14

Fleisher, Mindy

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

435 681, 514 12, 514834, 530381, 530382, 530829, 530830, A61K 3836, A61K 3516, C07K 14745, C07K 116

Patent

active

055939686

ABSTRACT:
A virus-inactivated Factor-Xa preparation with at least 100 units coagulation factor activity per mg protein is described, wherein this preparation is produced by activation of a corresponding starting material and subsequent treatment for the inactivation of infectious agents, particularly viruses. By incubation, the preparation obtained in this manner is transformed into a stable beta-Factor Xa preparation. In addition, the use of the present preparation for the treatment of hemophilia A inhibitor patients is disclosed.

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