Virulence genes, proteins, and their use

Details Virulence genes, proteins, and their use Virulence genes, proteins, and their use

2005-12-13

2005-12-13

Graser, Jennifer E. (Department: 1645)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

C435S029000, C435S004000, C424S200100

Reexamination Certificate

active

06974680

ABSTRACT:
A series of genes fromPseudomonas aeruginosaandKlebsiellaare shown to encode products that are implicated in virulence. The identification of these genes therefore allows attenuated microorganisms to be produced. Furthermore, the genes or their encoded products can be used to identify antimicrobial drugs, diagnostic methods for the identification of a pathogen-associated disease, and in the manufacture of vaccines.

REFERENCES:
patent: WO 02/101081 (2002-12-01), None
patent: WO 03/022881 (2003-03-01), None
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