Compositions – Compositions containing a single chemical reactant or plural... – Organic reactant
Patent
1988-01-15
1990-12-04
Bell, James J.
Compositions
Compositions containing a single chemical reactant or plural...
Organic reactant
424404, 514578, 514711, 514142, C11D 950
Patent
active
049752170
ABSTRACT:
Germicidal compositions for direct application to human skin are provided. The compositions include an organic acid, e.g., malic acid, and an anionic surfactant, e.g., a sodium alpha-olefin sulfonate, as active ingredients, and can optionally include an alcohol, e.g., specially denatured ethyl alcohol, as an additional active ingredient. When formulated as soaps and lotions, the compositions have been found to produce more than a 2.0 log reduction in bacteria applied to skin.
REFERENCES:
patent: 3023144 (1962-02-01), Greathouse et al.
patent: 3057467 (1962-10-01), Williams
patent: 3244636 (1966-04-01), Reller et al.
patent: 3278370 (1966-10-01), McCoy et al.
patent: 3408298 (1968-10-01), Baraville
patent: 3836044 (1974-09-01), Tilp et al.
patent: 3969258 (1976-07-01), Carandang et al.
patent: 4017002 (1977-04-01), Doyle et al.
patent: 4045364 (1977-08-01), Richter
patent: 4105782 (1978-08-01), Yu et al.
patent: 4105783 (1978-08-01), Yu et al.
Cowles, P. B., "Alkyl Sulfates: Their Selective Bacteriostatic Action", Yale Journal of Biology and Medicine, 11, 33-38, (1938).
Archiv fur Lebensmittelhygiene, 29, 81-120 (1978).
Dychdala, G. R., "Surface-Active Agents: Acid-Anionic Compounds", Disinfection, Sterilization, and Preservation, S. Block (ed.), 3rd Ed., pp. 330-333, (1983).
Newton, B. A., "Surface-Active Bactericides", Symposium for the Society for General Microbiology, No. 8, pp. 62-93, (1958).
Sobel, J. D. et al., "Nosocomial Pseudomonas cepacia Infection Associated with Chlorhexidine Contamination", Am. J. Med., 73, 185-186, (1982).
Fox, J. G., et al., "Nosocomial Transmission of Serratia marcesens in a Veterinary Hospital due to contamination by Benzalkonium Chloride", J. of Clin. Microbiol., 14, 157-f160, (1981).
McBride, M. E., "Microbial Flora of In-use Soap Products", Appl. and Environ. Microbiol., 48, 348-341, (1984).
Marrie, T. J., and Costerton, J. W., "Prolonged Survival of Serratia marcesens in Chlorhexidine", Appl. and Environ. Microbiol., 42, 1093-1102, (1981).
Draize, J. H., et al., "Methods for the Study of Irritation and Toxicity of Substances Applied Topically to the Skin and Mucous Membranes", Journal of Pharmacology and Experimental Therapeutics, 82, 377-390, (1944).
Aly, R. and Maibach, H. I., "A Comparison of the Antimicrobial Effect of 0.5% Chlorhexidine (HIBISTAT.RTM.) and 70% Isopropyl Alcohol on Hands Contaminated with Serratia marcescens", Clin. and Experi. Derm., 5, 197-201, (1980).
Hart, J. R., "Sarcosinate Surfactants in Skin Cleansers", Cosmetic technology, Jan. 1980.
Baker, Z., et al., "The Bactericidal Action of Synthetic Detergents", Journal of Experimental Medicine, 74, 611-621, (1941).
"Sagrosept Cloths", Schulke and Mayr GmbH, Robert-Kock Str. 2, 2000 Noderstedt, West Germany.
Brown-Skrobot Susan K.
Hossain Shafi U.
Kuenn Cary K.
Smith Kenneth R.
Bell James J.
Herrick William D.
Kimberly-Clark Corporation
Maycock William E.
LandOfFree
Virucidal composition, the method of use and the product therefo does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Virucidal composition, the method of use and the product therefo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Virucidal composition, the method of use and the product therefo will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-882082