Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1987-01-27
1989-06-20
Schain, Howard E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530418, 530421, 530380, 530395, 4352403, 514 8, C07K 1514, C07K 324
Patent
active
048410268
ABSTRACT:
Method and composition for providing a non-toxic, sterile, virally inactivated human transferrin preparation for use in cell culture systems. The method comprises saturation of the transferrin with an excess of iron, removal of free iron radicals and unwanted proteins, and pasteurization of the iron-bound transferrin substantially free of iron radicals.
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Islove et al., J. Exp. Med., 923-33 (1978), vol. 147.
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Pappenhagen Albert R.
Van Beveren Shirley M.
Aston David J.
Kushan Jeff P.
Miles Laboratories Inc.
Schain Howard E.
Simonton Pamela A.
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