Viral proteins capable of binding LAR

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

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C424S232100

Reexamination Certificate

active

06852486

ABSTRACT:
A poxvirus protein designated A41L binds to leukocyte common-antigen-related protein (LAR). A41L is a secreted protein that can be purified from the culture supernatant of cells infected with certain poxviruses, or produced using recombinant DNA techniques. A41L polypeptides and LAR polypeptides, and nucleic acids encoding them, are provided herein. Also provided are methods of using such polypeptides and nucleic acids.

REFERENCES:
patent: 5871740 (1999-02-01), Smith
patent: 6355252 (2002-03-01), Smith et al.
patent: 1092772 (2001-04-01), None
patent: WO 9837217 (1998-08-01), None
Qiao et al., Differential Effects of Leukocyte Common Antigen-related protein, The Journal of Biological Chemistry, vol. 176, No. 12, Issue of Mar. 23, 2001, pp. 9460-9467.*
Zabolotny et al., Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase, PNAS, vol. 98, No. 9, pp. 5187-5192.*
Pickup et al., Sequence of Terminal Regions of Cowpox virus DNA, PNAS USA, vol. 79, No. 23, Dec. 1, 1982, pp. 7112-7116.*
Yang et al. Leukocyte common-antigen-related tyrosine phosphatase receptor, Carcinogenesis, 2000, col. 21, No. 2, pp. 125-131.*
Carfi, A. et al., “Structure of a soluble secreted chemokine inhibitor vCCI (p35) from cowpox virus,”PNAS 96(22): 12379-12383, 1999.
Howard, S. et al., “Vaccinia virus homologues of the shope fibroma virus inverted terminal repeat proteins and a discontinuous ORF related to the tumor necrosis factor receptor family,”Virology 180: 633-647, 1991.
Martinez-Pomares, L. et al., “Mapping and investigation of the role in pathogenesis of the major unique secreted 35-kDa protein of rabbitpox virus,”Virology 206: 591-600, 1995.
Smith et al., “Poxvirus genomes encode a secreted, soluble protein that preferentially inhibits beta chemokine activity yet lacks sequence homology to known chemokine receptors,”Virology 236:316-327, 1997.

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