Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-09-19
2006-09-19
Kaushal, Sumesh (Department: 1633)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S069520, C435S320100, C435S325000, C435S455000, C435S252100, C435S471000, C530S300000
Reexamination Certificate
active
07109002
ABSTRACT:
The present invention relates to viral interleukin-6 (v-IL-6), which can be obtained by recombinant expression of the DNA of human herpesvirus type 8 (HHV-8), and which may be used in diagnosis and treatment of human diseases such as kaposi sarcoma, Castleman's disease, multiple myeloma, kidney cell carcinoma, mesangial proliferative glomerulonephritis or B cell lymphoma.
REFERENCES:
patent: 5200313 (1993-04-01), Carrico
patent: 5831064 (1998-11-01), Chang et al.
patent: 5861240 (1999-01-01), Ganem et al.
patent: 8800206 (1988-01-01), None
Neipel, F., et al “Human Herpesvirus 8 Encodes a Homolog of Interleukin-6”, Journal of Virology, vol. 71, No. 1, pp. 839-842 (1997).
Russo, J., et al., “Nucleotide Sequence of the Kaposi Sarcoma-Associated Herpesvirus (HHVB)”, Proc. Natl. Acad. Sci. USA. vol. 93. pp. 14862-14867 (1996).
Moore, P., et al., “Molecular Mimicry of Human Cytokine and Cytokine Response Pathway Genes by KSHV”, Science, vol. 274, pp. 1739-1744 (1996).
Zhong, W., et al., “Restricted Expression of Kaposi Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Genes in Kaposi Sarcoma”, Proc. Natl. Acad. Sci. USA, vol. 93, pp. 6641-6646 (1996).
Verma et al., Nature, 389, 1997, pp. 239-242.
Mullberg et al., J. Immunol., 164, 2000, pp. 4672-4677.
Hoischen et al., Eur. J. Biochem., 267, 2000, pp. 3604-3612.
Molden et al., J. Biol. Chem., 272, 1997, pp. 19625-19631.
Wan et al., J. Virology, 73, 1999, pp. 8268-8278.
Chang et al., Science, 266, 1994, pp. 1865-1869.
H.R. Maurer, in Animal Cell Culture—A Practical Approach, ed. R.I. Freshney, IRL Press Limited, Oxford, England, 1987, pp. 13-31.
Orkin et al., “Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy”, Dec. 1995.
Albrecht Jens Christian
Fleckenstein Bernhard
Friedman-Kien Alvin
Huang Yao Qi
Neipel Frank
BehringDiagnostics GmbH
Kaushal Sumesh
New York University School of Medicine
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