Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits
Patent
1995-10-25
1999-03-02
Saucier, Sandra E.
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Inactivation or attenuation; producing viral subunits
435 2, 4352861, A01N 102, C12N 706, C12M 302
Patent
active
058770054
ABSTRACT:
The invention involves the use of supercritical or near-critical fluids for the inactivation of viruses, especially enveloped or lipid protected viruses, and nonenveloped, protein encased viruses, viral-like particles and other pathogens in any matrix, but preferably in solutions containing biologically active proteinaceous products of natural or genetic engineering origin or in semi-solid or solid support matrices which are thermally labile or sensitive to conventional viral inactivation techniques. Novel apparatus also are provided.
REFERENCES:
patent: Re32695 (1988-06-01), Nahra et al.
patent: 4749522 (1988-06-01), Kamarei
patent: 5520943 (1996-05-01), Osajima et al.
patent: 5667835 (1997-09-01), Osajima et al.
Castor Trevor P.
Cosman Maury David
D'Entremont Peter Richard
Lander Arthur D.
Pelletier Michael Richard
Aphios Corporation
Saucier Sandra E.
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