Viral enhancer DNA segments

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide

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4351723, 4351721, 536 27, 935 36, C12P 2100, C12N 1500, C07H 1512

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047228970

ABSTRACT:
An enhancer DNA segment having an excellent action of enhancing the transcriptional efficiency of an incorporated gene in a cell, said segment being derived from a human papovavirus BK mutant designated as pm411, pm522 or pm525.
The enhancer DNA segment is useful for enhancing the expression of a gene encoding a biologically active substance in host eukaryotic cells.

REFERENCES:
Watanabe et al, Journal of Virology, vol. 42, pp. 978-985, Jun. 1982.
Khoury et al, Cell, vol. 33, pp. 313+314, Jun. 1983.

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