Viral detection liposomes and method

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S006120, C435S029000, C428S402200, C536S024320

Reexamination Certificate

active

07829272

ABSTRACT:
A method of generating pathogen detecting liposomes includes a step of providing molecular beacons with fluorescing components. The molecular beacons include either strands of RNA or DNA and the fluorescing components include an emitter and a quencher. The method further uses nanodroplet technology to encapsulate the molecular beacons within a lipid membrane. Subsequently, receptors are assembled in association with the membrane.

REFERENCES:
patent: 4661442 (1987-04-01), Lukens
patent: 2004/0248188 (2004-12-01), Sanders
patent: 2005/0123935 (2005-06-01), Haugland et al.
patent: 2006/0275854 (2006-12-01), Li et al.
patent: 2007/0269459 (2007-11-01), Coll Morales et al.
patent: 2008/0248492 (2008-10-01), Yamazaki et al.
patent: 2008/0303415 (2008-12-01), Suzuri et al.
Tyagi and Kramer. Molecular Beacons: Probes that Fluoresce upon Hybridization, Nature Biotechnology. 1996; 14:303-308.
Spear, PG. Herpes simplex virus: receptors and ligands for cell entry. Cellular Microbiology. 2004; 6(5):401-410.
Medina-Kauwe, LK. Endocytosis of adenovirus and adenovirus capsid proteins. Advanced Drug Delivery Reviews. 2003; 55: 1485-1496.
Lakadamyali, et al. Endocytosis of influenza viruses. Microbes and Infection. 2004; 6:929-936.
Kido, et al. Proteases Essential for Human Influenza Virus Entry into Cells and Their Inhibitors as Potential Therapeutic Agents. Current Pharmaceutical Design. 2007;13:405-414.
Lopez and Arias. Multistep entry of rotavirus into cells: a Versaillesque dance. TRENDS in Microbiology. 2004; 12(6): 271-278.
Wittlich, et al. Expression, purification, and membrane reconstitution of a CD4 fragment comprising the transmembrane and cytoplasmic domains of the receptor. Protein Expression and Purification. 2007; 55:198-207.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Viral detection liposomes and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Viral detection liposomes and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Viral detection liposomes and method will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4181290

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.