Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing
Reexamination Certificate
2007-03-06
2007-03-06
Campell, Bruce R. (Department: 1648)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
C424S185100, C424S186100, C424S232100
Reexamination Certificate
active
10503687
ABSTRACT:
The present invention relates to the identification and characterisation of a viral homologue (vCD30) of mammalian CD30. The vCD30 polypeptide is shown to have immunomodulatory activity and has various therapeutic applications.
REFERENCES:
Shchelkunov et al. Virol. 1998, vol. 243, No. 2, pp. 432-460.
Stanciu et al. Respiratory Research 2005, vol. 6, No. 67, pp. 1-7.
Legg et al. Am J. Respi. Crit. Care. Med. 2003, vol. 168, pp. 633-639.
Lazar et al. Molecular and Cellular Biology 1988, vol. 8, No. 3, pp. 1247-1252.
Smilek et al. Proc. Natl. Acad. Sci. USA, 1991, vol. 88, pp. 9633-9637.
Horrie et al. Immunology 1998, vol. 10, pp. 457-470.
Hamann et al. J. Immunol. 1996, vol. 156, pp. 1388-1391.
Chen et al., “Analysis of host response modifier ORFs of ectromelia virus, the causative agent of mousepox,”Virus Research, 66:155-173 (2000).
Panus et al., “Coxpox virus encodes a fifth member of the tumor necrosis factor receptor family: A soluable, secreted CD30 homologue,”PNAS, 99(12):8348-8353 (2002).
Saraiva et al., “CrmE, a Novel Soluable Tumor Necrosis Factor Receptor Encoded by Poxviruses,”Journal of Virology, 75(1):226-233 (2001).
Shchelkunov et al., “The Genomic Sequence Analysis of the Left and Right Species-Specific Terminal Region of a Cowpox Virus Strain Reveals Unique Sequences and a Cluster of Intact ORFs for Immunomodulatory and Host Range Proteins,”Virology, 243:432-260 (1998).
Database EMBL ‘Online’, D13 L protein,EBI Database accessionNo. P87599, XP002248019, May 1, 1997.
Alcami Antonio
Saraiva Margarida
Cambridge University Technical Services Limited
Campell Bruce R.
Klarquist & Sparkman, LLP
Li Bao Qun
LandOfFree
Viral CD30 polypeptide does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Viral CD30 polypeptide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Viral CD30 polypeptide will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3785665