Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-09
1996-11-05
Travers, Russell
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3135
Patent
active
055718361
ABSTRACT:
Viral attachment to target cells is inhibited by novel neuraminic acid compounds of the formula: ##STR1## wherein R.sup.1 is selected from the group consisting of hydrogen and acetyl; R.sup.2 is selected from the group consisting of hydrogen and methyl; and Y is selected from the group consisting of: ##STR2## The novel compounds bind virus particles and are substantially uncleaved by neuraminidase. Coupling of the novel compounds to a polymer further inhibits viral attachment.
REFERENCES:
Bovina et al 121 CA:149048w 1994.
Bovin Nicolai V.
Bryamova Nargiz E.
Gambaryan Alexandra S.
Matrosovich Mikhail N.
Mochalova Larisa V.
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