Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1996-08-15
1999-11-23
Smith, Lynette R. F.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4241991, 435236, 435237, A61K 3912, C12N 704, C12N 708
Patent
active
059895632
ABSTRACT:
A substantially avirulent vaccine against Porcine Reproductive and Respiratory Syndrome (PRRS) is provided, which effectively immunizes swine against the U.S. and European forms of the disease, together with a method of growing the viral agent in vitro, and a method of attenuating the virus for vaccine preparation.
REFERENCES:
patent: 4753884 (1988-06-01), Kit et al.
patent: 5683865 (1997-11-01), Collins et al.
Beare et al., "Further Studies in Man of Hsw1N1 Influenza Viruses," Journal of Medical Virology, 5:33-38 (1980).
Berendt et al., "Reaction of Squirrel Monkeys to Intratrachael Inoculation with Influenza/A/New Jersey/76 (Swine) Virus," Infection and Immunity, pp. 476-479 (1977).
Berendt et al., "Evaluation of Commercially Prepared Vaccines for Experimentally Induced Type/A/New Jersey/8/76 influenza Virus Infections in Mice and Squirrel Monkeys," The Journal of Infectious Disease, vol. 136, pp. S712-S718, Supplement (1977).
Bohl et al., "Isolation and Serotyping of Porcine Rotaviruses and Antigenic Comparison with Other Rotaviruses," Journal of Clinical Microbiology, pp. 105-111, (1984).
Bouillant et al., "Viral Susceptibility of a Cell Line Derived from the Pig Oviduct," Can. J. comp. Med., vol. 39, pp. 450-456, (1975).
Cabasso et al., "Propagation of Infectious Canine Hepatitis Virus in Tissue Culture. (20843)," P.S.E.B.M., v85, pp. 239-245, (1954).
Callebaut et al. "Antigenic Differentiation between Transmissible Gastroenteritis Virus of Swine and a Related Porcine Respiratory Coronavirus," J. gen. Virol.69, 1725-1730, (1988).
Charley, "Interaction of Influenza Virus With Swine Alveolar Macrophages: Influence of anti-virus Antibodies and Cytochalasin B," Ann. Virol. (Inst. Pasteur), 134 E, 51-59, (1983).
Dea et al., "Antigenic Variant of Swine Influenza Virus Causing Proliferative and Necrotizing Pneumonia in Pigs," J. Vet. Diagn. Invest., vol. No. 4, pp. 380-392 (Apr. 1992).
Dea et al., "Caracteristiques d'Isolats des virus influenza et de l'encephalomyocardite associes au Syndrome Reproducteur et Respiratoire Porcin (S.R.R.P.) au Quebec.sup.a," Le Medecin Veterinaire Du Quebec, vol. 21, No. 4, pp. 170-175, (Nov. 1991)(with English translation).
Easterday, "Swine Influenza," Diseases of Swine, 6th Edition, pp. 244-255, (1986).
Girard, et al., "Experimentally Induced Porcine Proliferative and Necrostising Pneumonia with an Influenza A Virus," The Veterinary Record, (1992) 130, 206-207, Mar. 7, 1992.
Gcurreau et al., "Diffusion Du Virus De La Grippe Du Porc (H1N1=Hsw1N1) En France," Ann. Virol. (Inst. Pasteur.), 132 E. 287-294 (1981).
Grizzard et al., "Experimental Production of Respiratory Tract Disease in Cebus Monkeys After Intratracheal or Intranasal Infection with Influenza A/Victoria/3/75 or Influenza A/New Jersey/76 Virus," Infection and Immunity, vol. 21, No. 1, pp. 201-205 (1978).
Imagawa et al., "Isolation of Foal Rotovirus in MA-104 Cells," Bull. Equine Res. Inst., No. 18, 119-128 (1981).
Johnson, "Feline Panleucopaenia Virus: IV.--Methods for Obtaining Reproducible in vitro Results," Res. vet. Sci., 8, pp. 256-265, (1967).
Kundin, "Hong Kong A-2 Influenza Virus Infection among Swine during a Human Epidemic in Taiwan," Nature, vol. 228, p. 857 and cover page.
Madec et al., "Consequences Pathologiques D'un Episide Grippal Severe (Virus Swine A/H.sub.1 N.sub.1) Dans Les Conditions Naturelles Chez La Truie Non Immune En Debut De Gestation," Comp. Immun. Microbiol. infect. Dis., vol. 12, No. 1/2, pp. 17-27, (1989).
McIntosh, "Diagnostic Virology", Chapter 17 of Fields Virology, Second Edition, vol. 1, pp. 411-437 (1990).
Meikieljohn et al., "Respiratory Virus Vaccine Evaluation and Surveillance," Semi-Annual Contract Progress report to the National Institute of Allergy and Infectious Diseases, 21 pgs., (Sep. 15, 1965 to Mar. 15, 1966).
Morin et al., "Sever proliferative and necrotizing pneumonia in pigs: A newly recognized disease," Can Vet J. vol. 31, pp. 837-839 (Dec. 1990).
Moore et al., "Porcine Proliferative and Necrotyzing Pneumonia Clinical Findings," Presented at American Association of Swine Practitioners. 22nd Annual Meeting, pp. 443-453 (Mar. 3-5, 1991).
Moore, C., "Porcine Proliferative and Necrotyzing Pneumonia Clinical Findings," Presented at American Association of Swine Practitioners. 22nd Annual Meeting, pp. 443-453 (Mar. 3-5, 1991).
Murakami et al., "Difference in growth behavior of human, swine, equine, and avian influenza viruses at a high temperature," Arch Virol, 100: 231-244 (1988).
Nakamura et al., "Studies on Swine Influenza. III. Propagation of Swine Influenza Virus in Explants of Respiratory Tract Tissues from Fetal Pigs," Studies on Swine Influenza, pp. 27-35, (1968).
Pirtle et al., "Morphologic Heterogeneity of a Strain of Swine Influenza Virus (A/Swine/Wisconsin/1/68, Hsw1N1) Propagated at Different Temperatures," Am J Vet Res, vol. 36, No. 1, pp. 1783-1787 (1975).
Poison et al., "Financial Implications of Mystery Swine Disease (MSD)," Livestock Conservation Institute Proceedings, Mystery Swine Disease Committee Meeting, pp. 8-27, Oct. 6, 1990.
Potgieter et al., "Isolation of Swine Influenza Virus in Oklahoma," JAVMA, vol. 171, No. 8, pp. 758-760, (1977).
Reed et al., "Persistent Respiratory Virus Infection in Tracheal Organ Cultures," Br. J. exp. Path., 50, 378-388, (1969).
Schmidt et al., "Infection by Influenza A Viruses of Trachael Organ Cultures Derived from Homologous and Heterologous Hosts," The Journal of Infectious Diseases, vol. 129, No. 1, pp. 28-36, (1974).
Stephen et al., "Swine Influenza Virus Vaccine: Potentiation of Antibody Responses in Rhesus Monkeys," pp. 1289-1290, (1977).
Stephen et al., "Swine Influenza Virus Vaccine: Potentiation in Rhesus Monkeys in Antibody Responses by a Nuclease Resistant Derivative of Poly I-Poly C," U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21701, 12 pages (double-sided), (1976).
Theil et al., "Isolation and Serial Propagation of Turkey Rotaviruses in a Fetal Rhesus Monkey Kidney (MA104) Cell Line," Avian Diseases, vol. 30, No. 1, pp. 93-104 (1985).
Tobita et al., "Plaque Assay and Primary Isolation of Influenza A Viruses in an Established Line of Canine Kidney Cells (MDCK) in the Presence of Trypsin," Med. Microbiol. Immunol., 162, 9-14 (1975).
Urasawa et al., "Sequential Passages of Human Rotavirus in MA-104 Cells," Microbiol. Immunol., vol. 25 (10), 1025-1035, (1981).
van Nieuwstadt et al., "Infection with porcine respiratory coronavirus does not fully protect pigs against intestinal transmissible gastroenteritis virus," The Veterinary Record, pp. 58-60, (1989).
van Nieuwstadt et al., "Use of two enzyme-linked immunosorbent assays to monitor antibody responses in swine with experimentally induced infection with porcine epidemic diarrhea virus," Am. J. Vet. Res., 52, 1044-1050 (Jul., 1991).
Webster et al., "Chemotherapy and Vaccination: a Possible Strategy for the Control of Highly Virulent Influenza Virus," Journal of Virology, vol. 55, No. 1, pp. 173-176, (1985).
Woods et al., "Antigenicity of Inactivated Swine Influenza Virus Concentrated by Centrifugation," Research Communications in Chemical Pathology and Pharmacology, vol. 13, No. 1, pp. 129-132, (1976).
Woods et al., "Experimental Challenge of Pregnant Gilts with Swine Influenza Virus After Vaccination," Research Communications in Chemical Pathology and Pharmacology, vol. 15, No. 4, pp. 787-795, (1976).
Woods et al., "Investigation of Four Outbreaks of Acute Respiratory Disease in Swine and Isolation of Swine Influenza Virus," Swine Influenza, vol. 5, No. 4, H.L.S., pp. 218-224, (1968).
Yamane et al., "Annual Examination of Influenza Virus Infection Among Pigs in Miyagi Prefecture, Japan: The Appearance of Hsw1N1 Virus," Acta. virol., 23: 240-248 (1979).
Dacso, C.C. et al., 1984, "Sporadic Occurrence of Zoonotic Swine Influenza Virus Infections", J. Clin. Microbiology 20(4):833-835.
Derbyshire, J.B., 1958, "Porcine Enterovirus Infections", Diseases of Swine, Fifth Edition, Chapter 20 pp. 265-271.
Goldfield, M. et al., 1977, "Influenza in New Jersey in 1976: Isolations of Influenza A
Chladek Danny W.
Gorcyca David E.
Harris Louis L.
Boehringer Ingelheim Vetmedica, Inc.
Devlin M-E. M.
Lee Datquan
Raymond R. P.
Smith Lynette R. F.
LandOfFree
Viral agent associated with mystery swine disease does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Viral agent associated with mystery swine disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Viral agent associated with mystery swine disease will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1218348