Vincamine derivatives, their preparation and therapeutical use

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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546 51, A61K 31445, C07D46100

Patent

active

042859492

ABSTRACT:
The new derivatives of vincamine according to this invention may be represented by the general formula ##STR1## in which R.sub.1 represents a halogen atom and R.sub.2 may represent a hydroxy group whereas R.sub.3 may represent a hydrogen atom, or R.sub.2 may form with R.sub.3 an additional bond.
The compounds may be used to treat cardio-circulatory, cerebro-vascular and respiratory insufficiencies.

REFERENCES:
patent: 3799933 (1974-03-01), Le Men et al.
patent: 3892755 (1975-07-01), Levy
patent: 3894028 (1975-07-01), Levy
patent: 3979395 (1976-09-01), Taccone
patent: 4033969 (1977-07-01), Sevenet et al.
patent: 4140777 (1979-02-01), Vegezzi
patent: 4145552 (1979-03-01), Heymes
patent: 4146643 (1979-03-01), Pfaffli
Subject Index (1967-1971) of Chemical Abstracts, subj., Vincamine, p. 328075.

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