Vincamine derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424267, C07D45900

Patent

active

040339696

ABSTRACT:
New compounds having the formula ##STR1## in which Y represents a hydrogen atom, in which case Z.sub.1 and Z.sub.2 represent simultaneously an oxygen atom, or Z.sub.1 represents a methoxycarbonyl radical and Z.sub.2 a hydroxy radical, or Y and Z.sub.2 form together a carbon-carbon bond and Z.sub.1 is a methoxycarbonyl radical, said compounds being additionally characterized by a cis-fusion of the D/E rings. Said new compounds and vincamine and certain of its derivatives are prepared from an enamine having the formula : ##STR2## in which R is H or C.sub.2 H.sub.5.

REFERENCES:
patent: 3454583 (1969-07-01), Kuehne
patent: 3770724 (1973-11-01), Warnant et al.
patent: 3830823 (1974-08-01), Castaigne

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