Vincamine 2-ketoglutarate and compositions containing vincamine

Details Vincamine 2-ketoglutarate and compositions containing vincamine Vincamine 2-ketoglutarate and compositions containing vincamine

1975-02-05

1976-09-21

Todd, G. Thomas

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

26029353, C07D40104

Patent

active

039820025

ABSTRACT:
The new compound vincamine 2-ketoglutarate of the formula: ##SPC1##
Is disclosed and is prepared by mixing 2-ketoglutaric acid and vincamine or a salt thereof in a solvent and recovering the resulting vincamine 2-ketoglutarate which has interesting properties as a vasodilator and brain oxygenator. The vincamine may be prepared by allowing a mixture of a solution of 16-epivincamine and a quaternary ammonium hydroxide to stand whereafter the vincamine is recovered.

REFERENCES:
patent: 3891640 (1975-06-01), Plat et al.

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