Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-09-12
2011-10-18
Jarrell, Noble (Department: 1622)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S478000
Reexamination Certificate
active
08039453
ABSTRACT:
The present invention relates to derivatives of vinca alkaloids. Pharmaceutical compositions containing these compounds as well as processes of preparation and treatment of various conditions are also disclosed.
REFERENCES:
patent: 5620985 (1997-04-01), Jacquesy et al.
patent: 0292463 (1988-11-01), None
patent: 8605491 (1986-09-01), None
Iuchi et al. Journal of Pharmacology Sciences, 2009, 109, pp. 573-582.
“What is arthritis? What causes arthritis”, http://www.medicalnewstoday.com/articles/7621.php, Accessed Dec. 3, 2010.
Burnham. Current Medicinal Chemistry, 2005, 12(17), 1995-2010.
Bau et al., “Crystal Structure of Vinblastine,” J. Chem. Soc. Perkin Trans. pp. 2079-2082 (2000).
Cros et al., “Experimental Antitumor Activity of Navelbine,” Seminars in Oncology 16(2)(Suppl. 4):15-20 (1989).
Keuhne et al., “Syntheses and Biological Evaluation of Vinblastine Congeners,” Organic and Biomolecular Chemistry 1:2120-36 (2003).
Lavoie et al., “Bioisosterism: A Rational Approach in Drug Design,” Chemical Reviews 96:3147-76 (1996).
Merck Index, “Vindesine,” 9982, 9986, 9987, and 9989.
Moncrief et al., “Structures of Leurocristine (Vincristine) and Vincaleukoblastine X-Ray Analysis of Leurocristine Methiodide,” Journal of American Chemical Society 87(21):4963-4964 (1965).
Neuss et al., “Vinca Alkaloids XXXIII[1]. Microbiological Conversions of Vincaleukoblastine (VLB, Vinblastine), an Antitumor Alkaloid fromVinca rosea,” Helvetica Chimica Acta 57(6):1886-90 (1974).
Sheng et al., “Synthesis and Biological Evaluation of C-12′ Substituted Vinflunine Derivatives,” Bioorganic & Medicinal Chemistry Letters 18:4602-4605 (2008).
Voss et al., “Synthesis and SAR of Vinca Alkaloid Analogues,” Bioorganic & Medicinal Chemistry Letters 19:1245-1249 (2009).
Guzzo Peter R.
Scott Ian L
Wolf Mark A.
Albany Molecular Research, Inc.
Jarrell Noble
LeClairRyan, a Professional Corporation
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