Vinca alkaloid pharmaceutical compositions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3144

Patent

active

049238760

ABSTRACT:
Disclosed herein are ready-to-use solutions comprising pharmaceutical compositions suitable for intravenous injection which are stable at room temperature. Pharmaceutical formulations of this invention comprise aqueous compositions of a pharmaceutically-acceptable vinca dimer salt, a citrate buffer and a preservative, wherein the composition pH is between 3.0 and 5.0.

REFERENCES:
patent: 3097137 (1960-05-01), Beer et al.
patent: 3205220 (1965-09-01), Svoboda et al.
patent: 4203898 (1980-05-01), Cullinan et al.
patent: 4259242 (1981-03-01), Rolski
patent: 4619935 (1986-10-01), Robison
Chen, J. R., 1982, Abstracts, 12:41.

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