Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-10-16
1977-03-15
Daus, Donald G.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07D51904
Patent
active
040123901
ABSTRACT:
Vinblastine, vincristine and leurosidine are converted to 3-carboxylic acids and 4-desacetyl-3-carboxylic acids, useful as intermediates to prepare aliphatic esters thereof.
REFERENCES:
patent: 3352868 (1964-04-01), Neuss et al.
patent: 3387001 (1968-06-01), Hargrove
patent: 3392173 (1968-07-01), Hargrove
Hargrove, Lloydia, 1964, pp. 340-345, vol. 27.
Cheng et al., "J. of Pharm. Sci.," 1970, pp. 1630-1632.
Daus Donald G.
Eli Lilly and Company
Rowe James L.
Smith Everet F.
Wheeler David E.
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