Vinblastine oxazolidinedione disulfides and related compounds

Details Vinblastine oxazolidinedione disulfides and related compounds Vinblastine oxazolidinedione disulfides and related compounds

1980-12-29

1982-12-07

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424262, C07D51904, A61K 31475

Patent

active

043626645

ABSTRACT:
Thioalkyl derivatives of vinblastine 3-spiro-5"-oxazolidine-2",4"-dione, mitotic inhibitors.

REFERENCES:
patent: Re30560 (1981-03-01), Miller et al.
patent: 4096148 (1978-06-01), Miller et al.
patent: 4199504 (1980-04-01), Conrad et al.
patent: 4203898 (1980-05-01), Cullinan et al.
Barnett et al., J. Med. Chem., 21, pp. 88-96 (1978).
Conrad et al., J. Med. Chem. 22, pp. 391-400 (1979).
McOmie, ed., Protective Groups in Organic Chemistry, Plenum Press, London & New York, 1973, pp. 236, 238.

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