Vinblastine derivatives and pharmaceutical composition containin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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540478, A61K 31475, C07D51904

Patent

active

048310387

ABSTRACT:
The invention relates to vinca (indole-dihydroindole) alkaloid derivatives, in which a fatty chain containing at least 7 aliphatic carbon atoms is present at least at the C.sup.3 /C.sup.4 -position.
The derivatives according to the present invention are useful as drugs.

REFERENCES:
patent: 4203898 (1980-05-01), Cullinan et al.
patent: 4388305 (1983-06-01), Trouet et al.
patent: 4639456 (1987-01-01), Trouet et al.
Richter Gedeon, Chemical Abstracts, vol. 97:216541c (1982).
Richter Gedeon, Chemical Abstracts, vol. 97:216542d (1982).

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