Vinblastin-23-oyl amino acid derivatives for use as antitumor ag

Details Vinblastin-23-oyl amino acid derivatives for use as antitumor ag Vinblastin-23-oyl amino acid derivatives for use as antitumor ag

1981-06-03

1983-06-14

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

2601125R, 2602444, 424262, A61K 31475, C07D51904

Patent

active

043883052

ABSTRACT:
Amino acid derivatives of vinblastine, including peptide derivatives, methods of their preparation and pharmaceutical compositions containing such vinblastine derivatives for use as antitumor agents are described.

REFERENCES:
patent: 3387001 (1968-06-01), Hargrove
patent: 4203898 (1980-05-01), Cullinan et al.

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