Veterinary treatment of ophthalmic disease in animals using...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S912000

Reexamination Certificate

active

06930127

ABSTRACT:
A composition and method for veterinary treatment of ophthalmic immune-mediated inflammatory conditions in animals such as conjunctival disorders of the third eyelid, keratoconjunctivitis sicca (KCS), chronic superficial keratitis (CSK), feline eosinophilic keratoconjunctivitis, allergic conjunctivitis, blepharoconjunctivitis, ocular rosacea, viral conjunctivitis, uveitis and phacoanaphylactic endophthalmitis involves the topical administration of tacrolimus to the eye in a pharmaceutically acceptable lubricant vehicle. The composition of the invention includes about 0.00001% to 10.0% tacrolimus by weight in a pharmaceutically acceptable oil-based solution or ointment and may be administered to the third eyelid of an affected animal.

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Christine Dresser, DVM; New Treatment for Dry Eye; The Nova: Rising Star Issue, p. 21, Nov., 2002.

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