Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Alkali or alkaline earth chloride
Patent
1997-11-12
1999-09-28
Pak, John
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Alkali or alkaline earth chloride
424438, 424600, 424617, 424646, 424679, 424681, 424682, 424686, 424687, 424688, 424689, 424693, 424696, 424702, 514 77, 514 79, 514 80, 514 81, 514 82, 514167, 514168, 514248, 514249, 514251, 514276, 514345, 514356, 514458, 514474, 514557, 514563, 514725, 514738, 514904, 514905, A61K 908, A61K 3300, A61K 3306, A61K 3314, A61K 3324, A61K 31525, A61K 3151, A23K 118
Patent
active
059584645
ABSTRACT:
A composition for preventing and treating milk fever in freshening cows, and a method of administering the composition. The basic composition is a mixture of water, calcium chloride, propylene glycol, B vitamins and minerals. The calcium content is lower than conventional calcium treatments used for this purpose. The propylene glycol gives the cow an energy boost and sweetens the taste so the cow does not object to it as it does to conventional gels and liquids. The B vitamins stimulate the cow's appetite. The minerals replace minerals lost in the milk and also help the cow absorb calcium. The composition of the present invention is in a liquid form and is preferably administered using a 200-300 cc drench gun. The end of the dispensing tube of the drench gun is placed between the teeth and cheek of the cow near the receptors that stimulate the esophageal groove reflex. A feature near the end of the dispensing tube causes a bulge in the cow's cheek which indicates the position of the dispensing tube within the cow's mouth. The composition stimulates the receptors and closes the esophageal groove, thereby allowing the liquid into the omasum where calcium is absorbed quicker than in the rumen. The cow swallows the liquid mixture in a near normal manner which prevents the solution from causing aspiration pneumonia.
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Goff, J.P. et al., "Oral Administration of Calcium Salts for Treatment of Hypocalcemia in Cattle," Journal of Dairy Science, vol. 76, No. 1, pp. 101-107, 1993.
Goff, J.P. et al., "Oral Calcium Paste Preparations for Treatment of Hypocalcemia: Vegetable Oil Versus Propylene Glycol as a Carrier," Journal of Dairy Science, vol. 76, Supp. 1, p. 295, 1993.
Goff et al., "Calcium Salts for Treating Hypocalcemia . . . ", J. Dairy Science, vol. 77 (5), 1994, pp. 1451-1456.
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