Vesicles and use thereof in an assay

Details Vesicles and use thereof in an assay Vesicles and use thereof in an assay

1987-10-09

1991-09-03

Saunders, David

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

264 41, 264 43, 264 46, 436829, G01N 33532

Patent

active

050454781

ABSTRACT:
Sacs comprising a compound having a hydrophilic peptide radical are prepared and are believed to have improved stability as a result of hydrogen bonding. The sacs, including a detectable marker and derivatized with a ligand may be used as a tracer in an assay.
At least a portion of the sac is formed from a compound having the following structural formula:

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patent: 4145410 (1979-03-01), Sears
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patent: 4708933 (1987-11-01), Huang et al.
patent: 4721612 (1988-01-01), Janoff et al.
patent: 4746508 (1988-05-01), Carey et al.
patent: 4762915 (1988-08-01), Kung et al.
Davis et al., Nature (London), 226, 360, 1970.
E. E. Conn et al., Outlines of Biochemistry, Fourth Edition, John Wiley & Sons, Inc., New York, 1976, p. 76.

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