Vesicle trafficking proteins

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07947804

ABSTRACT:
The invention provides three human vesicle trafficking proteins (VTP) and polynucleotides which identify and encode VTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of VTP.

REFERENCES:
Pevsner, J. et al., EMBL Accession No. Q15715 “Vacuolar Protein Sorting Homolog h-VPS45”, Nov. 1, 1996.
Piper, R.C. et al., “Yeast Vps45 is a Sec1p-like protein required for the consumption of vacuole targeted, post-Golgi transport vesicles”, Europ. J. Cell Biology, vol. 65, pp. 305-318 (1994).
Pevsner, J., “The Role of Sec1p-Related Proteins in Vesicle Trafficking in the Nerve Terminal”, J. Neurosci. Res., vol. 45, pp. 89-95 (1996).
Tellam, J.T. et al., “Identification of a Mammalian Golgi Sec1p-like Protein, mVps45”, J. Biol. Chem., vol. 272, pp. 6187-6193.
El Husseini, A. E-D. et al., “Molecular cloning of a mammalian homologue of the yeast vesicular transport protein vps45”, BB Acta, vol. 1325, pp. 8-12 (1997).
Rajasekariah, P. et al., “Molecular cloning and characterization of a cDNA encoding the human leucocyte vacuolar protein sorting (h1Vps45)”, Int. J. Biochem. Cell Biol., vol. 31, pp. 683-694 (1999).
Aalto, M., et al., “A Family of Proteins Involved in Intracellular Transport,”Cell, 68:181-182 (1992).
El-Husseini, A., et al., Molecular cloning of a mammalian homologue of the yeast vesicular transport protein vps45,Biochimica et Biophysica Acta1325:8-12 (1997).
Pevsner, J., et al., “Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking,”Gene, 183:7-14.
Niu, S., et al., Cloning and sequencing of a developmentally regulated avian mRNA containing the LEA motif found in plant seed proteins,Gene, 175:187-191 (1996).
Kuge, O., et al., “ζ-COP, a Subunit of Coatomer, Is Required for COP-coated Vesicle Assembly,”The Journal of Cell Biology, 123(6):1727-1734 (1993).
Tellam, J.T., et al., (GI 1703494), GenBank Sequence Database (Accession U66865), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (1996).
Tellam, J.T., et al., (GI 1703493), GenBank Sequence Database (Accession U66865), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (1996).
Niu, S., et al., (GI 969170),GenBank Sequence Database (Accession U31977), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (1996).
Niu, S., et al., (GI 969169),GenBank Sequence Database (Accession U31977), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (1996).
Kuge. O.,(GI 441486),GenBank Sequence Database (Accession X75935, National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (1993).
Kuge. O.,(GI 441485),GenBank Sequence Database (Accession X75935, National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (1993).
Adams, M.D. et al.,Nature377 (6547 Suppl.) 3-174 (1995).
Iadonato, S.P. et al., (g1808698) Accession No. AC000109, Sep. 11, 1997.
Iadonato, S.P. et al., (g1808699) Accession No. AC000110, Jan. 30, 1997.
GenBank Accession AA442417, “zv70e05.r1 Soares—total—fetus—Nb2HF8—9wHomo sapienscDNA clone”, submitted by Hillier et al., Jun. 2, 1997.
GenBank Accession U35246, “Human vacuolar protein sorting homolog h-vps45 mRNA, complete cds.”, submitted by Pevsner et al., Jan. 15, 1997.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Vesicle trafficking proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Vesicle trafficking proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vesicle trafficking proteins will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2655063

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.