Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-05-06
1998-11-10
Kemmerer, Elizabeth C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 6, 4352523, 4353201, 435325, 536 235, C12P 2100, C12N 121, C12N 1500, C07H 2104
Patent
active
058342419
ABSTRACT:
The present invention provides a human vesicle trafficking protein (HVTP) and polynucleotides which identify and encode HVTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing HVTP and for treating or preventing disorders associated with expression of HVTP.
REFERENCES:
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Adams et al. Genbank Record. Accession/Locus #T31927. Definition: Homo sapieus cDNA 5' end similar to none, 1995.
Lian, J.P. et al., "Boslp, an Integral Membrane Protein of the Endoplasmic Reticulum to Golgi Transport Vesicles, Is Required for Their Fusion Competence", Cell, 73: 735-745 (1993).
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Lian, J.P. et al., "Ypt1p implicated in v-SNARE activation", Nature, 372: 698-701 (1994).
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Hay, J.C. et al., "Mammalian Vesicle Trafficking Proteins of the Endoplasmic Reticulum and Golgi Apparatus", J. Biol. Chem., 271: 5671-5679 (1996).
Hay, J.C. et al., (Direct Submission), GenBank Sequence Database (Accession 1223898), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1223898).
Hay, J.C. et al., (Direct Submission), GenBank Sequence Database (Accession U42755), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1223897).
Corley Neil C.
Hillman Jennifer L.
Lal Preeti
Billings Lucy J.
Incyte Pharmaceuticals Inc.
Kemmerer Elizabeth C.
Mohan-Peterson Sheela
Romeo David S.
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