Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology
Reexamination Certificate
2006-12-05
2006-12-05
Romeo, David S (Department: 1647)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of regulating cell metabolism or physiology
C514S002600, C514S012200, C530S350000
Reexamination Certificate
active
07144732
ABSTRACT:
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
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Ingham Philip W.
McMahon Andrew P.
Tabin Clifford J.
Fish & Neave IP Group Ropes & Gray LLP
Gamett Daniel C
Imperial Cancer Research Technology Institute
President and Fellows of Harvard College
Romeo David S
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