Vertebrate apoptosis gene: compositions and methods

Details Vertebrate apoptosis gene: compositions and methods Vertebrate apoptosis gene: compositions and methods

1995-06-06

1998-11-10

Stanton, Brian R.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

4351723, 435243, 4353201, 435410, 536 231, 536 234, 536 241, 935 22, 935 66, 935 70, 935 72, C07H 2102, C07H 2104, C12N 510, C12N 1512

Patent

active

058343091

ABSTRACT:
The invention relates generally to compositions of and methods for obtaining and using a polypeptide other than BCL-2 that affects programmed vertebrate cell death. The invention relates as well to polynucleotides encoding those polypeptides, recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant polypeptides. The invention further provides methods for using the isolated, recombinant polypeptides in assays designed to select and improve substances capable of altering programmed cell death for use in diagnostic, drug design and therapeutic applications.

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