Vero cell-based influenza virus strains and vaccines

Details Vero cell-based influenza virus strains and vaccines Vero cell-based influenza virus strains and vaccines

2011-04-26

2011-04-26

Chen, Stacy B (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

C424S186100

Reexamination Certificate

active

07931906

ABSTRACT:
The present invention relates to isolated influenza virus strains suitable for increased vaccine production for mammals. The influenza virus strains contain at least one modified influenza protein that results in increased production of the influenza virus from a mammalian host cell, such as a vero cell. The present invention also relates to the vaccines produced from the influenza virus strains. The present invention further relates to isolated modified influenza proteins and isolated nucleic acid molecules that encode for the modified influenza proteins.

REFERENCES:
Nicolson et al., Vaccine, 2005, 23:2943-2952.

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