Verifiable absorption drug delivery form based on cyclodextrins

Details Verifiable absorption drug delivery form based on cyclodextrins Verifiable absorption drug delivery form based on cyclodextrins

2005-04-26

2005-04-26

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S103000, C536S124000

Reexamination Certificate

active

06884790

ABSTRACT:
Solid dosage forms are produced by absorbing solutions of drug:cyclodextrin inclusion complexes on absorbing matrices and then drying. The matrices may, but need not, disintegrate in water. The resulting forms are suitable for oral or sublingual administration, and also can be used in topical administrations to mucosa covered tissues. They are particularly suitable for sublingual administration because the eluted, nondisintegrated matrix (e.g., absorbing paper) can be recovered and checked for completion of elution. This enables documentation that effective absorption occurred from the mouth cavity.

REFERENCES:
patent: 5134127 (1992-07-01), Stella et al.
patent: 54506 (1991-03-01), None

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