Vented vial stopper for processing freeze-dried products

Drying and gas or vapor contact with solids – Process – Freeze-drying

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34242, 220404, F26B 2500

Patent

active

055968147

ABSTRACT:
An vented vial stopper for use in processing freeze-dried products is provided. The stopper includes a vent passageway that is covered with a waterproof and moisture vapor permeable membrane to allow the venting of moisture during the freeze-drying process. The membrane also extends to cover most or all of the exposed surface of the stopper to protect the stopper from chemical attack during processing.

REFERENCES:
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patent: 3953566 (1976-04-01), Gore
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patent: 4096227 (1978-06-01), Gore
patent: 4187390 (1980-02-01), Gore
patent: 4878597 (1989-11-01), Haast
patent: 5164139 (1992-11-01), Fujioka et al.
patent: 5309649 (1994-05-01), Bergmann et al.
J. M. Barbaree, A. Sanchez, and G. N. Sanden, "Problems in Freeze-drying: II. Cross-Contamination During Lyophilization," vol. 26 of Developments in Industrial Microbiology, A Publication of the Society of Indusrial Microbiology, 1985, Chapter 27, pp. 407-409.

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