Vented vial method of minimizing contamination of freeze-dried p

Drying and gas or vapor contact with solids – Process – Freeze-drying

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34298, F26B 506

Patent

active

055221556

ABSTRACT:
The present invention relates to a lyophilization process involving the use of a cap intended for vials or use therewith for containers that are subjected to lyophilization conditions where the cap, which may be resiliently helped in place or screwed on, includes a plug member movable within a fluid passageway in the cap, the plug member while positioned in the fluid passageway is movable between a first upwardly extending venting position and second downwardly engaging, sealing position whereby fluid from the vial or container is precluded from flowing through the fluid passageway in the cap.

REFERENCES:
patent: 3454178 (1969-07-01), Bender
patent: 4060911 (1977-12-01), Weller et al.
patent: 4883507 (1989-11-01), Rey et al.
patent: 5309649 (1994-05-01), Bergmann et al.

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