Venlafaxine in the treatment of hypothalamic amenorrhea in non-d

Details Venlafaxine in the treatment of hypothalamic amenorrhea in non-d Venlafaxine in the treatment of hypothalamic amenorrhea in non-d

1995-01-30

1996-04-09

Acquah, Samuel A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

C-o-group doai

564157, 564219, 564336, 549443, 549444, 514646, 514653, 514659, 514727, 514729, 514899, A61K 31045, A01N 3100

Patent

active

055062709

ABSTRACT:
This invention provides a method for treating hypothalamic amenorrhea in a non-depressed female mammal by administering to the mammal an effective amount of a hydroxycycloalkanephenethyl amine compound of the following structural formula: ##STR1## in which A is a moiety of the formula ##STR2## wherein the dotted line represents optional unsaturation;
R.sub.1 is hydrogen or alkyl;
R.sub.2 is alkyl;
R.sub.4 is hydrogen, alkyl, formyl, or alkanol;
R.sub.5 and R.sub.6 are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, dialkylamino, alkanamido, halo, trifluoromethyl, or taken together, methylene dioxy;
R.sub.7 is hydrogen or alkyl; and
n is 0, 1, 2, 3, or 4;
or a pharmaceutically acceptable salt thereof.

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