Vehicle composition containing 1-substituted azacyclopentan-2-on

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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424 88, 424181, 424238, 424240, 424244, 424251, A61K 3130, A61K 3170, A61K 3171, A61K 31505

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active

044447620

ABSTRACT:
Compositions useful for carrying physiologically active agents such as therapeutic agents through skin and other body membranes comprising the agent and an effective, non-toxic amount of a compound having the structural formula ##STR1## wherein R' is H or a lower alkyl group, m is 3-7, N is 0-17 and R is --CH.sub.3, phenyl or substituted phenyl or ##STR2## with the proviso that if m is 3 and R is --CH.sub.3, then n is not 0-6.

REFERENCES:
patent: 3085931 (1963-04-01), Darlington
patent: 3551554 (1970-12-01), Herschler
patent: 3891757 (1976-11-01), Higuchi

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