Vehicle composition containing 1-substituted azacycloalkan-2-one

Details Vehicle composition containing 1-substituted azacycloalkan-2-one Vehicle composition containing 1-substituted azacycloalkan-2-one

1980-04-04

1982-02-23

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

424 88, 424181, 424238, 424240, 424244, 424251, A61K 3130, A61K 3170, A61K 3171, A61K 31505

Patent

active

043168930

ABSTRACT:
Compositions useful for carrying physiologically active agents such as therapeutic agents through skin and other body membranes comprising the agent and an effective, non-toxic amount of a compound having the structural formula ##STR1## wherein R' is H or a lower alkyl group, m is 3-7, N is 0-17 and R is --CH.sub.3, phenyl or substituted phenyl or ##STR2## with the proviso that if m is 3 and R is --CH.sub.3, then n is not 0-6.

REFERENCES:
patent: 3332938 (1967-07-01), Mayhew et al.
patent: 3551554 (1970-12-01), Herschler
patent: 3891757 (1975-06-01), Higuchi
Chemical Abstracts 73:102083d (1970).
Chemical Abstracts 74:87436w (1971).
Chemical Abstracts 75:24868p (1971).
Swain et al., J. of Org. Chem., vol. 18, pp. 1087-1091 (1953).

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