VEGF-C ΔR 226 ΔR 227 mutants and uses thereof

Details VEGF-C ΔR 226 ΔR 227 mutants and uses thereof VEGF-C ΔR 226 ΔR 227 mutants and uses thereof

2007-10-30

2010-10-05

Saoud, Christine J (Department: 1647)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C435S325000, C435S243000, C514S002600, C514S012200, C536S023500, C530S399000

Reexamination Certificate

active

07807412

ABSTRACT:
Provided are purified and isolated VEGF-C polypeptides capable of binding to at least one of KDR receptor tyrosine kinase (VEGFR-2) and Flt4 receptor tyrosine kinase (VEGFR-3); analogs of such peptides that have VEGF-C-like or VEGF-like biological activities or that are VEGF or VEGF-C inhibitors; polynucleotides encoding the polypeptides; vectors and host cells that embody the polynucleotides; pharmaceutical compositions and diagnostic reagents comprising the polypeptides; and methods of making and using the polypeptides.

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