Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1994-12-09
1996-11-19
Mosher, Mary E.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 43525233, 4353201, 435 691, 435 697, 435 696, 536 234, C12P 2100, C12N 1531, C12N 1562, C12N 121
Patent
active
055761950
ABSTRACT:
The invention relates to DNA coding for a pectate lyase signal peptide which has been inserted into plasmids to create secretion vectors which are capable of producing a chosen protein by directing transport across the bacterial membrane. The secretion vectors have been used to secrete extracellular thaumatin and extracellular antibody fragments. The proteins produced by these vectors have biological activity. The thaumatin is properly folded and the antibody fragments are capable of binding antigens on target cancer cells.
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Sun
Better Marc
Lei Shau-Ping
Robinson Randy R.
Wilcox Gary L.
Mosher Mary E.
Xoma Corporation
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