Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-07-10
1998-10-20
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 4352523, 43525233, C12P 2102, C12N 1563, C12N 121
Patent
active
058245057
ABSTRACT:
The present invention relates to vectors for cloning, in a host cell, hirudin or an analog of hirudin, characterized in that it comprises the gene for encoding hirudin or an analog of hirudin, and the elements for the expression of this gene in said host cell, said coding gene beginning, after the starting sequence, by an Ile codon and a Thr codon. This invention also relates to the process for the preparation of hirudin or analogs of hirudin as well as the hirudin or anologs of hirudin obtained.
REFERENCES:
patent: 4517294 (1985-05-01), Bock et al.
patent: 4578355 (1986-03-01), Rosenberg
patent: 5232912 (1993-08-01), Krstenansky
patent: 5422249 (1995-06-01), Liersch et al.
patent: 5516656 (1996-05-01), Misawa et al.
patent: 5573929 (1996-11-01), Misawa et al.
Dodt et al. FEBS 165:180-84, 1984 (Jan.).
Bagdy et al. In. Methods in Enzymology, vol. XLV, pp. 669-678, 1976, Academic Press, NY.
Chemical Abstracts, vol. 100, No. 152937g "The complete amino acid sequence of hirudin, a thrombin specific inhibitor. Application of color carboxymethylation." J. Dodt et al. FEBS Lett. (1984) 165(2):180-184.
"Plasmid vectors for positive selection of DNA inserts controlled by the pL promoter, repressor and antitermination function", by A. Honigman and A.B. Oppenheim, Gene, vol. 13, 1981, pp. 289-298.
Chemical Abstracts, vol. 100, No. 152937g "The complete amino acid sequence of hirudin, a thrombin specific inhibitor. Application of color carboxy-methylation." J. Dodt et al. FEBS Lett. (1984) 165(2):180-184.
"Plasmid vectors for positive selection of DNA inserts controlled by the pL promoter, repressor and antiterminatin function", by A. Honigman and A.B. Oppenheim, Gene, vol. 13, 1981, pp. 289-298.
Dodt et al. FEBS 165:180-84, 1984 (Jan.).
Bagdy et al. In. Methods in Enzymology, vol. XLV, pp. 669-678, 1976., Academic Press, NY.
Courtney Michael
Harvey Richard
LeCocq Jean-Pierre
Tolstoshev Paul
Lau Kawai
Transgene S.A.
Wax Robert A.
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