Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-07
1998-03-17
Guzo, David
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4352541, 43525411, 4352543, 4352561, 4353201, 4351723, 536 231, 536 241, C12N 1580, C12N 1563, C07H 2104, C12P 2100
Patent
active
057285470
ABSTRACT:
Novel vectors are disclosed for use in filamentous fungi such as Aspergillus sp. in particular, whereby protein coding regions may be inserted therein to achieve expression or expression followed by secretion of the coded protein from the host. Signal peptide sequences and promoter sequences valuable for this purpose are disclosed as are expression vectors containing coding regions native or foreign to the fungal host. In accordance with the invention, a filamentous fungus such as Aspergillus may be provided with foreign or natural coding regions associated with foreign or natural promoter sequences and optionally signal peptide sequences which can be used to control the expression and/or secretion of the proteins encoded by these coding regions.
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Buxton Francis Paul
Davies Roger Wayne
Gwynne David Ivor
Pickett Mark Hudson
Scazzocchio Claudio
Guzo David
Royal Gist-Brocades N.V.
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