Vectors derived from baculovirus and use for transferring...

Details Vectors derived from baculovirus and use for transferring... Vectors derived from baculovirus and use for transferring...

2006-03-28

2006-03-28

Vogel, Nancy (Department: 1636)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C435S320100

Reexamination Certificate

active

07018628

ABSTRACT:
The invention concerns novel recombinant viruses and their use for gene-transfer into nerve cells of vertebrates. The invention also concerns pharmaceutical compositions comprising said recombinant viruses. More particularly, the invention concerns novel vectors derived from baculoviruses and their use for treating diseases of the nervous system of vertebrates.

REFERENCES:
patent: WO 98/11243 (1998-03-01), None
patent: WO9812311 (1998-03-01), None
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Kelly, Experimental Neurology, 144, 157-159, 1997.
Brooks et al., J. Neuroscience Methods, 80, 137-147, 1998.
Boyce, F.M. et al., Baculovirus-mediated Gene Transfer Into Mammalian Cells, PNAS 93:2348-2352 (Mar. 1996).
Shoji, I. et al., Efficient Transfer into Various Mammalian Cells, including Non-Hepatic Cells, By Baculovirus Vectors, Journal of General Virology, 78(10):2657-2664 (1997).
Hofmann, C. et al., Efficient Gene Transfer Into Human Hepatocytes by Baculovirus Vectors, PNAS USA 92:10099-10103 (1995).
Sandig, V. et al., Gene Transfer into Hepatocytes and Human Liver Tissue by Baculovirus Vectors, Human Gene Therapy, 7:1937-1945 (1996).
Barsoum, J. et al., Efficient Transduction of Mammalian Cells bya Recombinant Baculovirus Having the Vesicular Stomatitis Virus G. Glycoprotein, Human Gene Therapy, 8:2011-2018 (1997).

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