Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2005-10-04
2005-10-04
McKelvey, Terry (Department: 1636)
Chemistry: molecular biology and microbiology
Vector, per se
C435S235100
Reexamination Certificate
active
06951755
ABSTRACT:
The present invention provides a recombinant adenovirus comprising coat proteins that lack native binding. In particular, the present invention provides a recombinant adenovirus comprising a penton base protein and a fiber protein, wherein the penton base protein and the fiber protein lack native binding. The present invention further provides a recombinant adenovirus comprising (a) a penton base protein that lacks native binding and (b) a nonnative amino acid sequence that binds a cell-surface binding site.
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Brough Douglas E.
Kovesdi Imre
Wickham Thomas J.
GenVec, Inc.
McKelvey Terry
Vogel Nancy
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