Vectors and host cells expressing prepromotilin and motilin-asso

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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4352523, 43525231, 43525233, 4353201, C12N 1570, C12N 1574, C12N 1579, C12N 1585

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050064690

ABSTRACT:
cDNA encoding a precursor peptide for motilin has been retrieved from porcine gut tissue. The precursor protein contains a motilin-associated peptide (MAP) sequence conjugated to the motilin peptide through a trypsin-like cleavage site. The MAP is useful in regulating alimentary physiology in vertebrates. The DNA provides a means to obtain the corresponding DNAs in other vertebrate species, including humans. It also makes available recombinant motilin, motilin precursor, and MAP of any desired species.

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