Vector system

Details Vector system Vector system

2008-09-02

2008-09-02

Guzo, David (Department: 1636)

Chemistry: molecular biology and microbiology

Process of mutation, cell fusion, or genetic modification

Introduction of a polynucleotide molecule into or...

C435S320100, C435S455000, C435S325000, C424S093100, C424S093200, C424S093600, C536S023100, C536S023720, C536S024200

Reexamination Certificate

active

10873573

ABSTRACT:
The present invention provides a vector system comprising a mutated post-transcriptional regulatory element. In particular, the present invention relates to a mutated WPRE sequence that can efficiently express nucleotides of interest in a retroviral vector system. The present invention also relates to methods of delivering and expressing nucleotides of interest to a target cell.

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