Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2007-08-21
2007-08-21
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S320100, C435S325000, C435S366000, C435S455000
Reexamination Certificate
active
10408456
ABSTRACT:
Provided are retroviral vector genomes and vector systems comprising the genomes. In particular, a retroviral vector genome comprising two or more NOIs, operably linked by one or more Internal Ribosome Entry Site(s); a lentiviral vector genome comprising two or more NOIs suitable for treating a neurodegenerative disorder; and a lentiviral vector genome which encodes tyrosine hydroxylase, GTP-cyclohydrolase I and, optionally, Aromatic Amino Acid Dopa Decarboxylase are provided.
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Azzouz Mimoun
Kingsman Alan John
Martin-Rendon Enca
Mazarakis Nicholas D.
Rohll Jonathan
Frommer & Lawrence & Haug LLP
Guzo David
Kowalski Thomas J.
Oxford Biomedia (UK) Limited
Yvon Anne-Marie C.
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