Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2006-01-17
2006-01-17
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S471000, C435S476000, C435S320100, C435S254110, C435S455000, C435S461000, C536S023100, C536S023200, C536S023700
Reexamination Certificate
active
06987026
ABSTRACT:
The present invention is directed to a recombinant vector for transforming yeast and a process for transforming yeast thereby, more particularly to a recombinant vector comprising a gene encoding a mutated L41 protein having cycloheximide-resistant activity and a ribosomal DNA. The recombinant vector and the process for transforming thereby of the present invention is applicable to the efficient and stable integration of desired foreign DNA into yeast genome, thus providing useful tools for the production of a natural pigment, astaxanthin.
REFERENCES:
patent: WO 94/06918 (1994-03-01), None
patent: WO 97/23633 (1997-03-01), None
I.G. Kim et al., Mar. 31, 1999, GenBank Accession No. AF004672.
I.G. Kim et al., Mar. 18, 1999, GenBank Accession No. AF016256.
E. Mutoh et al., “Inducible Expression of a Gene Encoding an L41 Ribosomal Protein Responsible for the Cycloheximide-Resistant Phenotype in the YeastCandido maltosa,” Journal of Bacteriology, 1995, 177(18):5383-5386.
K. Kondo et al., “A Transformation System for the YeastCandido utilisUse of a Modified Endogenous Ribosomal Protein Gene as a Drug-Resistant Marker and Ribosomal DNA as an Integration Target for Vector DNA,” Journal of Bacteriology, 1995, 177(24):7171-7177.
P. Dehoux et al., “Natural cycloheximide resistance in yeast The role of ribosomal protein L41,” Eur. J. Biochem, 1993, 213:841-848.
L. Del Pozo et al., “Two different genes fromSchwanniomyces occidentalisdetermine ribosomal resistance to cycloheximide,” Eur. J. Biochem, 1993, 213:849-857.
CH. T. Roberts et al., “A Cycloheximide-resistant Mutant ofTetrahymena Pyriformis,”Experimental Cell Research, 1973 81:312-316.
I.-G. Kim et al., “Cloning of the Ribosomal Protein L41 Gene ofPhaffia rhodozymaand Its Use as a Drug Resistance Marker for Transformation,” Applied and Environmental Microbiology, 1998, 64(5):1947-1949.
J. Wery et al., “High copy number integration into the ribosomal DNA of the yeastPhaffia rhodozyma,” Gene, 1997, 184:89-97.
S. Kawai et al., “Drastic Alteration of Cycloheximide Sensitivity by Substitution of One Amino Acid in the L41 Ribosomal Protein of Yeasts,” Journal of Bateriology, 1992, 174(1):254-262.
Choi Eui-Sung
Choi Seok Keun
Jang Jae Kweon
Lee Seung Jae
Lee Yoon Hyoung
Gates & Cooper LLP
Guzo David
Haitai Confectionery Co., Ltd.
Korea Institute of Science and Technology
LandOfFree
Vector for the transformation of Phaffia rhodozyma and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Vector for the transformation of Phaffia rhodozyma and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vector for the transformation of Phaffia rhodozyma and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3557853