Vector for integration of heterologous sequences into...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...

Reexamination Certificate

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Details

C435S235100, C435S320100, C435S471000, C435S091410, C435S325000, C435S490000, C536S023720

Reexamination Certificate

active

07150874

ABSTRACT:
A new DNA vector is disclosed comprising a nucleic acid sequence useful for inserting heterologous sequences into the genome of poxviruses by homologous recombination. Also disclosed are recombinant poxviruses carrying heterologous coding sequences transferred by the DNA vector.

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Antoine et al (Virology 244:365-396, 1998).
Meyer et al, Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence, “Journal of General Virology”, 1991 pp. 1031-1038.

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