Vector comprising signal peptide-encoding DNA for use in Bacillu

Details Vector comprising signal peptide-encoding DNA for use in Bacillu Vector comprising signal peptide-encoding DNA for use in Bacillu

1987-01-30

1990-12-11

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4351723, 43525233, 435320, 935 11, 935 29, 935 73, 935 74, C12N 1570, C12N 1575

Patent

active

049770896

ABSTRACT:
A novel promoter, ribosome-binding site-encoding DNA, and a number of signal peptide-encoding DNA sequences are described for use in Bacillus and other host cells. The compounds are useful in constructing expression vectors for use in Bacillus and other host cells and drive expression and secretion of proteins such as nuclease and human growth hormone. In addition, a general method for obtaining cells with increased abilities to express and secrete heterologous gene products is described.

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